Stange KC, Miller WL, Etz RS. The role of primary care in improving population health. Milbank Q. 2023;101(S1):795–840.
Google Scholar
Starfield B, Shi L, Macinko J. Contribution of primary care to health systems and health. Milbank Q. 2005;83(3):457–502.
Google Scholar
Bonfim D, Belotti L, de Almeida LY, Eshriqui I, Velasco SRM, Monteiro CN, et al. Challenges and strategies for conducting research in primary health care practice: an integrative review. BMC Health Serv Res. 2023;23(1):1380.
Google Scholar
Bierman AS, Tong ST, McNellis RJ. Realizing the dream: the future of primary care research. Ann Fam Med. 2022;20(2):170–4.
Google Scholar
Cuschieri S. The CONSORT statement. Saudi J Anaesth. 2019;13(Suppl 1):S27-s30.
Google Scholar
Zülke A, Luck T, Pabst A, Hoffmann W, Thyrian JR, Gensichen J, et al. AgeWell.de – study protocol of a pragmatic multi-center cluster-randomized controlled prevention trial against cognitive decline in older primary care patients. BMC Geriatr. 2019;19(1):203.
Google Scholar
Zülke AE, Pabst A, Luppa M, Oey A, Weise S, Fankhänel T, et al. Effects of a multidomain intervention against cognitive decline on dementia risk profiles-results from the AgeWell.de trial. Alzheimers Dement. 2024;20(8):5684–94.
Google Scholar
Röhr S, Zülke A, Luppa M, Brettschneider C, Weißenborn M, Kühne F, et al. Recruitment and baseline characteristics of participants in the AgeWell.de Study-A pragmatic cluster-randomized controlled lifestyle trial against cognitive decline. Int J Environ Res Public Health. 2021;18(2):408.
Google Scholar
Buckley D, McHugh SM, Riordan F. What works to recruit general practices to trials? A rapid review HRB. Open Res. 2023;6:13.
Foster JM, Sawyer SM, Smith L, Reddel HK, Usherwood T. Barriers and facilitators to patient recruitment to a cluster randomized controlled trial in primary care: lessons for future trials. BMC Med Res Methodol. 2015;15:18.
Google Scholar
Glasgow RE, Battaglia C, McCreight M, Ayele R, Maw AM, Fort MP, et al. Use of the reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) framework to guide iterative adaptations: applications, lessons learned, and future directions. Front Health Serv. 2022;2: 959565.
Google Scholar
Jolles MP, Fort MP, Glasgow RE. Aligning the planning, development, and implementation of complex interventions to local contexts with an equity focus: application of the PRISM/RE-AIM Framework. Int J Equity Health. 2024;23(1):41.
Google Scholar
Alonge O. How to leverage implementation research for equity in global health. Glob Health Res Policy. 2024;9(1):43.
Google Scholar
Kivipelto M, Ngandu T, Laatikainen T, Winblad B, Soininen H, Tuomilehto J. Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study. Lancet Neurol. 2006;5(9):735–41.
Google Scholar
Physicians NAoSHI. Arztsuche [German]. Berlin; Germany: National Association of Statutory Health Insurance Physicians; 2025 [Available from: https://www.kbv.de/html/arztsuche.php.
Physicians NAoSHI. Arztsuche– Terminservice 116117 [German]. Munich, Schleswig-Holstein, Saxony-Anhalt; Germany: National Association of Statutory Health Insurance Physicians; 2025 [Available from: https://arztsuche.116117.de/.
Physicians NAoSHI. Gesundheitsdaten– PraxisPanel [German]. Berlin; Germany: National Association of Statutory Health Insurance Physicians 2025 [Available from: https://gesundheitsdaten.kbv.de/cms/html/17016.php.
Pomerania AoSHIPM-W. Arztsuche [German]. Greifswald; Germany: Association of Statutory Health Insurance Physicians Mecklenburg-Western Pomerania; 2025 [Available from: https://www.kvmv.de/service/arztsuche/.
Saxony AoSHIP. Arztsuche [German]. Leipzig; Germany: Association of Statutory Health Insurance Physicians Saxony; 2025 [Available from: https://asu.kvs-sachsen.de/arztsuche/.
Institute RK. Revision of the German Index of Socioeconomic Deprivation (GISD): Updated Version 2 – 2022.. Berlin; Germany: Robert Koch Institute; 2022.
Institute RK. German Index of Socioeconomic Deprivation (GISD) [German]. Berlin; Germany; 2025.
Kroll LE, Schumann M, Hoebel J, Lampert T. Corrigendum: regional health differences-developing a socioeconomic deprivation index for Germany. J Health Monit. 2017;2(2):114.
Google Scholar
Michalski N, Reis M, Tetzlaff F, Herber M, Kroll LE, Hövener C, et al. German index of socioeconomic deprivation (GISD): revision, update and applications. J Health Monit. 2022;7(Suppl 5):2–23.
Google Scholar
Naqvi A. POLARSPIKE: Stata module for polar spike graphs. 2024.
Green JA. Too many zeros and/or highly skewed? A tutorial on modelling health behaviour as count data with Poisson and negative binomial regression. Health Psychol Behav Med. 2021;9(1):436–55.
Google Scholar
White IR, Royston P, Wood AM. Multiple imputation using chained equations: issues and guidance for practice. Stat Med. 2011;30(4):377–99.
Google Scholar
McCarthy C, Pericin I, Smith SM, Moriarty F, Clyne B. Recruiting general practitioners and older patients with multimorbidity to randomized trials. Fam Pract. 2023;40(5–6):810–9.
Google Scholar
Wangler J, Jansky M. Primary care involvement in clinical research-prerequisites, motivators, and barriers: results from a study series. Arch Public Health. 2024;82(1):41.
Google Scholar
Messner DA, Moloney R, Warriner AH, Wright NC, Foster PJ, Saag KG. Understanding practice-based research participation: the differing motivations of engaged vs. non-engaged clinicians in pragmatic clinical trials. Contemp Clin Trials Commun. 2016;4:136–40.
Google Scholar
Tong SF, Ng CJ, Lee VKM, Lee PY, Ismail IZ, Khoo EM, et al. Decision making process and factors contributing to research participation among general practitioners: a grounded theory study. PLoS ONE. 2018;13(4): e0196379.
Google Scholar
Tawo S, Gasser S, Gemperli A, Merlo C, Essig S. General practitioners’ willingness to participate in research: a survey in central Switzerland. PLoS ONE. 2019;14(3): e0213358.
Google Scholar
van der Gaag WH, van den Berg R, Koes BW, Bohnen AM, Hazen LM, Peul WC, et al. Discontinuation of a randomised controlled trial in general practice due to unsuccessful patient recruitment. BJGP Open. 2017;1(3):bjgpopen17X101085.
Google Scholar
Sumanen M, Reho T, Heikkilä T, Mäntyselkä P, Halila H, Mattila K. Research orientation among general practitioners compared to other specialties. Scand J Prim Health Care. 2021;39(1):10–6.
Google Scholar
Sanftenberg L, Stofella J, Mayr K, Nassehi A, Härdtlein A, Stark S, et al. Expectations of general practitioners on a practice based research network in Germany- a qualitative study within the Bavarian research practice network (BayFoNet). BMC Prim Care. 2024;25(1):10.
Google Scholar
Sanftenberg L, Schnaidt AL, Eck S, Schneider A, Bucher E, Kurotschka PK, et al. Experiences of general practice teams and their patients with clinical research-a mixed-methods process evaluation of the Bavarian research practice network (BayFoNet). BMC Prim Care. 2025;26(1):59.
Google Scholar
Bauer A, Virnau L, Kroeber ES, Lingner H, Bleckwenn M, Frese T, et al. Exploring participants’ characteristics and self-assessed readiness to conduct clinical trials in general practice – baseline analysis of the RaPHaeL practice-based research network. Scand J Prim Health Care. 2025;43(2):270–80.
Google Scholar
Young RA, Fulda KG, Suzuki S, Hahn KA, Espinoza AM, Marshall JD, et al. The influence of research compensation options on practice-based research network (PBRN) physician participation: a North Texas (NorTex) PBRN study. J Am Board Fam Med. 2011;24(5):562–8.
Google Scholar
Yawn BP, Pace W, Dietrich A, Bertram S, Kurland M, Graham D, et al. Practice benefit from participating in a practice-based research network study of postpartum depression: a national research network (NRN) report. J Am Board Fam Med. 2010;23(4):455–64.
Google Scholar
Kersten S, Kuschick D, Bräsigk A, Polanc A, Salm S. [Active participation of medical assistants in primary care research in Germany]. Z Evid Fortbild Qual Gesundhwes. 2025.
Aggarwal M, Hutchison B, Wong ST, Katz A, Slade S, Snelgrove D. What factors are associated with the research productivity of primary care researchers in Canada? A qualitative study. BMC Health Serv Res. 2024;24(1):263.
Google Scholar
Goldstein KM, Vogt D, Hamilton A, Frayne SM, Gierisch J, Blakeney J, et al. Practice-based research networks add value to evidence-based quality improvement. Healthc (Amst). 2018;6(2):128–34.
Google Scholar
Koskela TH. Building a primary care research network – lessons to learn. Scand J Prim Health Care. 2017;35(3):229–30.
Google Scholar
Virnau L, Braesigk A, Deutsch T, Bauer A, Kroeber ES, Bleckwenn M, et al. General practitioners’ willingness to participate in research networks in Germany. Scand J Prim Health Care. 2022;40(2):237–45.
Google Scholar
Fernald DH, Jortberg BT, Hessler DM, Wearner R, Dickinson LM, Fisher L, et al. Recruiting primary care practices for research: reflections and reminders. J Am Board Fam Med. 2018;31(6):947–51.
Google Scholar
Moffat KR, Shi W, Cannon P, Sullivan F. Factors associated with recruitment to randomised controlled trials in general practice: a systematic mixed studies review. Trials. 2023;24(1):90.
Google Scholar
Modigh A, Sampaio F, Moberg L, Fredriksson M. The impact of patient and public involvement in health research versus healthcare: a scoping review of reviews. Health Policy. 2021;125(9):1208–21.
Google Scholar
Heinmüller S, Schneider A, Linde K. Quantity, topics, methods and findings of randomised controlled trials published by German university departments of general practice – systematic review. Trials. 2016;17(1):211.
Google Scholar
Huas C, Petek D, Diaz E, Muñoz-Perez MA, Torzsa P, Collins C. Strategies to improve research capacity across European general practice: the views of members of EGPRN and Wonca Europe. Eur J Gen Pract. 2019;25(1):25–31.
Google Scholar
Dania A, Nagykaldi Z, Haaranen A, Muris JWM, Evans PH, Mäntyselkä P, et al. A review of 50 years of international literature on the external environment of building practice-based research networks (PBRNs). J Am Board Fam Med. 2022;35(4):762–92.
Google Scholar
Fagnan LJ, Dolor R. PBRN conference highlights stakeholder engagement and dangerous ideas. Ann Fam Med. 2015;13(5):496–8.
Google Scholar
Hickner J, Green LA. Practice-based research networks (PBRNs) in the United States: growing and still going after all these years. J Am Board Fam Med. 2015;28(5):541–5.
Google Scholar
Kristoffersen ES, Bjorvatn B, Halvorsen PA, Nilsen S, Fossum GH, Fors EA, et al. The Norwegian PraksisNett: a nationwide practice-based research network with a novel IT infrastructure. Scand J Prim Health Care. 2022;40(2):217–26.
Google Scholar
O’Regan A, Hayes P, O’Connor R, Casey M, O’Dwyer P, Culhane A, et al. The university of limerick education and research network for general practice (ULEARN-GP): practice characteristics and general practitioner perspectives. BMC Fam Pract. 2020;21(1):25.
Google Scholar
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